Abstract

Background and aims: The dead rate of hand, foot and mouth disease is very high. Aims: To predict the risk of mortality in severe hand-foot and mouth disease, through death cases and survival cases to compare hospital clinical laboratory index (ratio of blood sugar, white blood cells, neutral particles, the lymphocytes and amino terminal brain natriuretic peptide precursor (NT - proBNP))? Methods: rom March to July 2012, a total of 295 hospitalized children enrolled for this retrorspective study. Results: Different NT - proBNP level group, an elevated level of scale differences, and there is statistical significance. Elevated blood sugar has 174, accounts for 58.98%, the proportion of different NT - proBNP level in children with high blood sugar is different, and there is statistical significance. As NT - proBNP levels, white blood cell count and blood sugar levels increasing children’s mortality also will increase. white blood cell count, blood sugar levels and NT - proBNP level as independent variable Logistics more factors regression analysis, the NT - proBNP level and WBC count become independent risk factors of severe hand, foot and mouth disease. Conclusions: in clinical suspected or confirmed after the hand-foot and mouth disease, to keep track of white blood cell count, blood sugar and NT - proBNP level, on the one hand, to prevent hand, foot and mouth disease early from mild to severe, on the other hand can through early intervention to reduce complications and mortality.

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