Abstract 327: A Comprehensive Echocardiogram Study in Postural Orthostatic Tachycardia Syndrome

Abstract

Background and Purpose: The Postural Orthostatic Tachycardia Syndrome (POTS) affects primarily young women. POTS is a form of dysautonomia affecting millions around the world. The aim of this study is to determine the echocardiographic findings in POTS patients. Methods: 173 POTS patients were randomly selected and underwent echocardiogram results were reviewed and performed cumulative distribution of echocardiogram results in to top 10 percentile to see the abnormalities. Results: Out of 173 patients, 96% are females (n=166; age 29.20 ± 9.26), 4% are males (n=7; age 28.50 ± 13.64) Our findings (mean ± SD). RVDD (2.37 cm ± 0.30 cm), LVED (4.34 cm ± 0.35 cm), IVS (0.82 cm ± 0.12 cm), LVEF (63.7%±2.61%), LVES (2.93 cm ± 0.25 cm), LVPW (0.83 cm ± 0.13 cm) , LVOT Dia (1.82 cm ± 0.20 cm) AO Root (2.70 cm ± 0.31 cm) , LA Dia ( 3.13 cm ± 0.36 cm) ,AV Vel (1.12 m/sec ± 0.13 m/sec), LVOT Vel (0.83 m/sec ± 0.31 m/sec), Mean Gradient (2.81mmHg ± 0.68 mmHg), Peek Gradient (4.91 mmHg ± 1.40 mmHg), AVA (2.65 cm2 ± 0.44 cm2),E Vel (0.77 m/sec ± 0.13 m/sec), A Vel (0.54 m/sec ± 0.10 m/sec), E/A Ratio (1.45 ± 0.36), Mean Gradient (0.83 mmHg ± 0.29 mmHg), Peak Gradient (2.21 mmHg ± 0.82 mmHg), PHT (48.25 m/sec ± 11.13 m/sec), MVDT (151.40 m/sec ± 31.44 m/sec) , MVA (4.85 cm2 ± 1.12 cm2), MR Mild in 82 % patients ,TV Vel (0.61 m/sec ± 0.13 m/sec), RAP (est) (10 mmHg ± 0 mmHg), TR Vel (20.78 m/sec ± 5.62 m/sec), RSVP (est) (29.04 ± 4.54),TR Mild in 86 % Patients.PV Vel ( 0.72 m/sec ± 0.16 m/sec). Top 10 percentile parameters are follows RVDD 2.75 cm, LVED 4.79 cm, IVS 0.97 cm, LVEF 67.04 %, LVES 3.25 cm, LVPW 0.97 cm, LVOT Dia 2.08 cm, Ao Root 3.10 cm, LA Dia 3.59 cm AV Vel 1.29 m/sec , LVOT Vel 1.23 m/sec , Mean Gradient 3.68 mmHg, Peek Gradient 6.70 mmHG,AVA 3.21 cm2. E Vel 0.94 m/sec , A Vel 0.67 m/sec , E/A Ratio 1.91 , Mean Gradient 1.20 mmHg, Peak Gradient 3.26 mmHg, PHT 62.51 m/sec , MVDT 191.69 m/sec, MVA 6.29 cm2, TV Vel 0.78 m/sec, RAP (est) 10mmHg, TR Vel 27.98 m/sec, RSVP (est) 34.81,PV Vel 0.93 m/sec. Conclusion: POTS patients have normal echocardiographic parameters however even the top 10 percentile of these patients had smaller LVEDD. Similarly the internal dimensions of cardiac chambers does appear to be smaller though still within accepted normal parameters. Further studies should be taken to better define this subgroup.