Abstract

Introduction: Current guidelines require a 50 mm compression depth for manual chest compression. During mechanical chest compression, however, because of the design of each device, whether this depth yields the most optimal hemodynamic efficacy remains to be tested. In this study, we investigated the effects of compression depth on hemodynamics efficacy during mechanical CPR with the Weil Mini Chest Compressor in a porcine model. Hypothesis: There is no significant difference in hemodynamic efficacy between compression depth of 30 mm and 50 mm during mechanical CPR with the Weil Mini Chest Compressor. Methods: Ten male domestic pigs weighing 34±2 kg were utilized. Ventricular fibrillation was electrically induced and untreated for 7 min. The animals were then randomized to receive compression depth of 30 mm or 50 mm. Coincident with the start of precordial compression, the animals were mechanically ventilated at a rate of 10 breaths per minute. Defibrillation was attempted by a single 150 J shock. If resuscitation was not successful, CPR was resumed for 2 mins prior to the next defibrillation until either successful resuscitation or for a total of 15 mins. Results: All animals were successfully resuscitated. There were no differences in coronary perfusion pressure (CPP), end-tidal carbon dioxide (ETCO2) and carotid blood flow (CBF) between the two groups (Table). A significantly less rib fracture was observed in the 30 mm group [0 (0-0) vs 1.2 (0-2), p<0.05]. Conclusion: Similar hemodynamic efficacy was observed between 30 and 50 mm compression depth during mechanical CPR with the Weil Mini Chest Compressor.

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