Abstract 269: Development of Acute Heart Failure Following Cardiac Catheterization in Patient’s With Pre-Existing Peripheral Artery Disease

Abstract

Background Peripheral artery disease has long been considered a CHD risk equivalent resulting in increased CAD, angina, CHF, and MI. Regardless, it is not known if PAD results in increased likelihood of acute complications following cardiac catheterization. Methods The medical records of 3817 patients undergoing cardiac catheterization at a university medical center were reviewed. Development of acute heart failure 72 hours after the procedure was compared to pre-existing medical conditions including peripheral artery disease using multiple logistic regression analysis. Results in the table below are reported as odds ratios with 95% confidence interval. Chi-square was measured comparing PAD with post procedure heart failure. Relative risk reported with 95% confidence interval. Results As shown below, there was a statistically significant difference between development of acute heart failure up to 72 hours after cardiac catheterization in patients with pre-existing PAD as well as history of hyperlipidemia. Chi-square demonstrated 22% of patients who developed heart failure also had pre-existing PAD (χ 2 (1,N=3816)=6.336, p =0.012). Relative risk of developing heart failure with pre-existing PAD was 1.782 (95% CI 1.13-2.80). Conclusion We have demonstrated in this retrospective analysis of 3817 patients, an increased risk of developing heart failure in patients with pre-existing PAD and dyslipidemia following cardiac catheterization. These results further justify optimal lipid management as an integral component of cardiovascular health, not only in relation to chronic disease, but also in the presence of acute injury. Legend PAD = Peripheral Artery Disease