Abstract
Primary hyperparathyroidism is the third most common endocrine disease, while association with Non-Hodgkin's Lymphoma is extremely rare. Both conditions can initially present with hypercalcemia. Here we present a case of 62-year-old female with recurrent syncope as initial complaint which was found to be secondary to hypercalcemia. There was elevated PTH, and she underwent parathyroidectomy with good intraop reduction of PTH but still had hypercalcemia. She was lost to follow-up and presented after 2 months with paraplegia. On evaluation she had abnormal cytology that was suggestive of leukemia. Further evaluation with bone marrow biopsy and flow cytometry revealed NHL. Association of nonendocrine cancers with parathyroid tumors is well established though pathogenesis is not yet clear. This emphasizes the importance of postoperative follow-up of primary hyperparathyroidism patients for early detection of associated cancers.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
