Abstract 221: Degenerative Neurological Comorbidities In Patients Hospitalized With Congestive Heart Failure

Abstract

BACKGROUND/OBJECTIVES: Chronic heart failure (CHF) has recently been known to be one of the most important public health concerns and a challenge to cardiovascular disease researchers, having increasing incidence and prevalence rates of CHF in industrialized countries. Although there are several sources of data on the congestive heart failure in selected populations, there are less few studies regarding the comorbidity of degenerative neurological disorders in patients diagnosed with congestive heart failure. METHODS: Cross-sectional data of a population-based nationwide inpatient CHF (797,113) subjects, average age (73 years) were analyzed to determine the prevalence of CHF and association of major neurological conditions in the inpatients admitted with CHF. The International Classification of Disease ICD-9 codes were used (CHF - 4280, Alzheimer - 3310, Parkinson- 3320 and Multiple Sclerosis - 340) for the selection. RESULTS: The overall gender-prevalence of CHF was 47% (n = 377,580) for males and 53% (n = 419,481) for females. Inpatients with CHF also had Alzheimer (n = 22,521; 31.65%), Parkinson (n = 10,969; 15.42%), and Multiple Sclerosis (n = 1,620; 2.28%). The prevalence of CHF strongly increased with age, less than 1% (n = 1,299) for subjects < 1 year age to ~4% (n = 31,488) among 82 year old subjects. The regression results for patients who were admitted with CHF as their primary complaints (71,130) showed a significance difference between patients who died in the hospital and most inpatients’ characteristics for age (p = .000), race (p = .000), hospital total charge (p = .000) and median household income (p = .015). However, gender (p = .090) was not statistically significant at p < .05. CONCLUSION: The prevalence of CHF increase appears higher in males than in female gender in this study. Patient age, economic status and hospital charges showed significant results with the mortality rate of the patients hospitalized in 2010. The associated degenerative neurological conditions in these inpatients could be attributed to other comorbidities and progressive neurological/degenerative disorders prevalent in elderly populations.