Abstract 2209: HPV non-vaccination due to safety concerns/side effects: Variations in vaccination intentions by Parent-Child Gender, National Immunization Survey - Teen, 2010 - 2019

Abstract

Abstract Background: Gender-generated disparities in HPV vaccination uptake have the potential to further perpetuate existing disparities in HPV-associated cancers. This study examines the influence of parent-child gender on intent to not vaccinate against HPV due to safety/side effect concerns. Methods: Study data was from the National Immunization Survey-Teen (2010 - 2019). Weighted prevalence of intention to refuse HPV vaccination due to safety/side effect concerns were stratified by parent-child gender. Multivariable logistic regressions were used to examine for associations between intentions to refuse HPV vaccination due to safety concern/side effects and parent-child gender. Results: Over the study period, intentions to refuse HPV vaccination due to safety concerns rose among all parent-child gender pairings but was highest among respondent mothers when pertaining to their unvaccinated daughters. Results revealed statistically significant increased likelihood of having intentions to refuse HPV vaccination due to safety concerns among all parent-child combinations, compared to father-son pairs. These odds were consistently highest among mother-daughter pairs; 9.25 times more likely (95% CI: 6.34-13.51) than father-son pairs in 2010. In 2019, compared to father - son pairs, fathers were 1.94 (95% CI: 1.21-3.12) times more likely to report intention to not vaccinate against HPV for their daughters; while mothers were 2.23 (95% CI: 1.57-3.17) times more likely to report intentions to refuse HPV vaccination for their sons; and 2.87 (95% CI: 2.02-4.07) more likely for their daughters. Conclusions: Intentions to refuse HPV vaccination due to safety concern/side effects varied by gender of the responding parent and pertinent child. Study findings are persistent and constantly increased over a 10-year period. Interventions aimed at correcting gender-based misperceptions, as well as to counter misinformation about the safety of the HPV vaccine are warranted. Citation Format: Onyema Chido-Amajuoyi, rajesh talluri, Inimfon Jackson, Sahil Shete, Joel Fokom Domgue, Sanjay Shete. HPV non-vaccination due to safety concerns/side effects: Variations in vaccination intentions by Parent-Child Gender, National Immunization Survey - Teen, 2010 - 2019 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2209.