Abstract 18751: Emerging Frontiers in Hypertension Management: Consensus on Novel Approaches for Optimal Control

Abstract

Introduction: To establish a comprehensive consensus statement on hypertension management, incorporating contemporary evidence and drawing from the valuable real-world experiences of Indian physicians and cardiologists Methods: A virtual collaborative educational initiative was convened in May 2023, through a series of 8 nationwide virtual interactive meetings (n=87) at the forefront of hypertension care (3B Consensus Group). The cumulative clinical experience was approximately 2,500-man-years, who rated their level of agreement for 10 questions with each item on a 5-point Likert scale. This was preceded by a contemporary evidence-based discussion on the contemporary updates for hypertension. Weighted mean for the Likert scale was calculated and consensus was pre-defined as a score > 100. GraphPad 9.5.1 and ANOVA were used for statistical analysis. Results: The highest agreement score was for, hypertension is an important cardiovascular risk factor in CKD (127.1), bisoprolol with conventional treatment is efficacious for managing MI and cardiac insufficiency (126.8), because of considerable variability in BP response to different drugs, personalized treatment approaches are essential to optimize the effectiveness of BP reduction (118.3), research is warranted to explore the importance of salt awareness in patients with hypertension (117.4), beta blockers including bisoprolol in the treatment of MI complicated with cardiac insufficiency effectively reduce cardiotoxicity, enhance myocardial response (114.4), treatment guided by ABPM can enhance outcomes (102.7) (Figure). The highest mean response scores (±SD, 95% CI) for consensus were for strongly agree (52.6±28.6, 95% CI 32.1 to 73) followed by agree (50.8±13.4, 95% CI 41.2 to 60.4) Conclusions: The physicians and cardiologists establish hypertension management consensus, emphasizing cardiovascular risk, bisoprolol efficacy, personalized treatment, salt awareness, and ABPM