Abstract 1761: Inhibition of PI3K/AKT/mTOR signaling by a dual PI3K/mTOR inhibitor (LY3023414) potentiates the antitumor efficacy of the Chk1 inhibitor prexasertib (LY2606368) in models of human high-grade serous ovarian cancer (HGSOC)

Jack Dempsey,Christoph Reinhard,Jennifer Stephens,Louis Stancato,Aimee Lin,Philip Iversen,Wenjuan Wu,Greg Donoho,Ann Mcnulty,Ricardo Martinez

doi:10.1158/1538-7445.sabcs18-1761

Abstract 1761: Inhibition of PI3K/AKT/mTOR signaling by a dual PI3K/mTOR inhibitor (LY3023414) potentiates the antitumor efficacy of the Chk1 inhibitor prexasertib (LY2606368) in models of human high-grade serous ovarian cancer (HGSOC)

Jack Dempsey, Christoph Reinhard + Show 8 more

https://doi.org/10.1158/1538-7445.sabcs18-1761

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Publication Date: Jul 1, 2019

#Human High-grade Serous Ovarian Cancer #Chk1 Inhibitor Prexasertib + Show 8 more

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Abstract 1761: Inhibition of PI3K/AKT/mTOR signaling by a dual PI3K/mTOR inhibitor (LY3023414) potentiates the antitumor efficacy of the Chk1 inhibitor prexasertib (LY2606368) in models of human high-grade serous ovarian cancer (HGSOC)

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