Abstract

A recent study has shown that serum phosphate (SP) may be a prognostic indicator for poor neurological outcomes in cardiac arrest patients. We aimed to confirm the hypothesis that a higher SP level predicts a poor neurological outcome of cardiac arrest, even in elderly patients. This retrospective observational study included post-cardiac arrest patients aged ≥65 years who were admitted to three hospitals in urban areas in South Korea from December 2013 to February 2020. Patient characteristics, laboratory values, and neurological outcomes at 28 days were collected from patients’ medical records. The primary outcome was poor neurological outcome (CPC scores 3-5) at 28 days. Of the 389 eligible patients, 334 had poor neurological outcomes. SP levels were higher in those with poor neurological outcomes (7.31 vs . 5.01, p<0.001). Multivariate logistic regression analysis showed that SP levels were independently associated with neurological outcomes. Higher SP levels are associated with poor neurological outcomes after cardiac arrest in the elderly population.

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