Abstract
There is increasing evidence that psychosocial interventions can influence neuroendocrine and immune responses in people affected by cancer. However, an under-researched area is whether music interventions, such as singing, can also be catalysts for such effects. We carried out a multicentre single-arm study to assess the impact of singing in three populations affected by cancer: carers (n = 72), bereaved carers (n = 66) and patients (n = 55). Participants took part in one hour of group singing, completing visual analogue mood scales, stress scales and providing saliva samples testing for cortisol, beta-endorphin, oxytocin and ten cytokines before and after. Across all five centres and in all three participant groups, singing was associated with significant reductions in stress and improvements in mood (p β -endorphin and connectedness (p
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