Abstract 17028: Characteristics and Short-Term Outcome of Patients in the Program “Get With the Guidelines” - One Vietnamese Center Registry

Abstract

Background: “Get with the guidelines HF” is a program with the aim of properly applying heart failure treatment recommendations into clinical practice and improving the outcome of patients. This study evaluated the initial result of the implementation of the program in one Vietnamese center. Method: This is a prospective, one-center, observational registry in Hanoi Heart Hospital, Vietnam. Hospitalized heart failure patients over 18 years old with reduced and mild reduced left ventricular ejection fraction (LVEF) were enrolled. Data included demographic characteristics, comorbidities, discharge medications, and post-discharge appointment plans. Results: From September 2021 to December 2022, 749 patients were included in the study with a mean age of 65. The male and female ratio was 56.1% and 43.9% respectively. 65.3% of the patients had reduced LVEF and 34.7% had mild reduced LVEF. Coronary heart disease was the most popular comorbidity and was diagnosed in 44.6% of patients. At discharge, after excluding drug contraindications, the rate of prescribing of RASi drugs (ACEi, ARB or ARNI), beta-blocker, mineralocorticoid receptor antagonists (MRA), SGLT2i were 97.56%, 92.86%, 96.15%, 57.14%, respectively in Q4.2021. At discharge, the rate of using these 4 drugs in Q4.2022 was 99.15%, 100%, 100%, and 85.19%, respectively. The rate of patients receiving all 4 GDMT drugs according to ACC/AHA guidelines in Q4.2021 and Q4 2022 was 28.8% và 41.4%. The percentage of patients using 3 and 2 GDMT drugs in the times mentioned above was 33.3% and 35.4% and 24.2% and 14.8%, respectively. Short-term follow-up showed that 30-day re-admission was 2.94% and the 30-day mortality after discharge was 0%. Conclusion: “Get with the guidelines” helps to implement guidelines to daily practice, especially the use of GDMT drugs, and gives promising results to improve the outcome for patients with heart failure. Keywords: heart failure, GDMT, Get with the guideline