Abstract
Abstract: No prior data is available for the comparative analyses on various anthropometric measures and coronary artery calcium score (CACS) progression in healthy low risk multiethnic population. Methods: The MESA (Multi-Ethnic Study of Atherosclerosis) study is a prospective cohort study of 6,814 self-identified White, African-American, Hispanic, or Chinese participants free of clinical cardiovascular disease at baseline. Incident CAC was defined as no CAC at baseline with development of CAC upon subsequent visits. CACS progression was defined as change in CAC volume score upon follow up visit in participants who had detectable CAC at baseline. Anthropometric measures at baseline were compared for their predictive value for incident CAC (analyzed using adjusted logistic regression analysis) and CACS progression (analyzed using adjusted median regression analyses). (See Table 1 for adjustments) Results: See Table 1 Conclusion: Measures of central obesity (especially, waist circumference and waist-hip ratio) have stronger association with both incident CAC and CACS progression among low risk multiethnic population compared to other anthropometric measures.
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