Abstract 16622: Methodological Study for Validation of a Protocol for Behavioral Change in Patients on Warfarin: EmpoderACO

Abstract

Introduction: To achieve stable control in warfarin therapy is challenging in clinical practice. Patients′ active participation is essential to promote self-care and medication adherence. We sought to build a conceptual map to substantiate the validation of EmpoderACO, in Brazilian Portuguese, a protocol for behavior change for patients on warfarin. Methods: This methodological study involved the development of a conceptual map focused on identifying self-care domains in warfarin users. Its content guided the development and validation of a behavior change protocol which comprised the following steps: definition of instrument objectives; construction and selection of items; construction and measurement of response scales; iv) structuring and assessment of content validity. The content validity was assessed by a committee of judges (CJ) and calculated by content validity coefficient (CVC). We used the software CmapTools (version 6.04, 2020) to build the conceptual map. Ethical approval 65928316.3.0000.5149. Results: Self-care domains in the conceptual map were divided into three categories: understanding and satisfaction with drug therapy; reduction of adverse events; promotion of well-being and healthy habits. The use of the conceptual map allowed the development of the final version of EmpoderACO with 27 items. A total of 34 specialists composed the multiprofessional CJ that analyzed the validity content. The overall average of CVC was ≥0.91, including relevance (0.92), adequacy (0.92) and clarity (0.91). Conclusions: The protocol EmpoderACO may contribute to a global approach of patients on warfarin to improve patient′s understanding of drug therapy, self-care behaviors and design of patient-centered care. The application of empowerment principles may be of particular utility in vulnerable populations living in low- and middle-income countries where warfarin is still widely prescribed for oral anticoagulation. Fig. 1 Conceptual map