Abstract 16094: Depressive Disorder and Quality of Life in Patients With Heart Failure

Abstract

Background According to the WHO 17.9 million people die every year owing to cardiovascular disease. Due to the increase in prevalence, heart failure (HF) is an important public health problem with more than 23 million people; its prevalence is expected to increase 46% by 2030. The presence of depression can affect up to 21.5% patients with HF, deteriorating quality of life with an increase in hospitalization and mortality rates. Aims Evaluate the factors associated with depressive symptoms and quality of life in patients with HF. Methods: Observational, analytical, transversal study with secondary analysis of 153 patients with HF treated in an outpatient clinic, considering baseline characteristics, echocardiogram parameters and depressive/quality of life PHQ-9 and Minnesota scales for univariate and bivariate analysis. Results: There was an association between the compromise of NYHA III-IV vs NYHA I-II functional class with: moderate to severe degree of depression (44,44% vs 24,9%) and impaired quality of life (61.11% vs 26.54%) p≤ 0.001, respectively. Likewise, statin use was associated with less depression (30.23% vs 11.82% p=0.006) and quality of life improvement (32,56% vs 14,55% p=0.012) respectively, this was independent of psychosocial support. Atrial fibrillation had a significant association with depression (p=0.030) and history of cerebrovascular disease (p=0.009). Conclusion: Depression is an important and common comorbidity that often coexist in patients with HF and are associated with poor quality of life. It is important to screen for depressive symptoms in these patients with the goal to provide appropriate treatment and avoid negative outcomes.