Abstract 15934: Trends and Disparities in Patients Admitted With Bradyarrhythmias: Insights From the National Inpatient Sample 2016-2020

Abstract

Introduction: Bradyarrhythmias are caused by a dysfunction in the cardiac conduction system at the level of the sinus node, the atrioventricular node, or the His/Purkinje system. We aimed to investigate national trends and outcomes in patients with bradyarrhythmias, grouped as sinus node dysfunction, atrioventricular block, and conduction disorder (with 1:1 AV conduction). Methods: We utilized the National Inpatient Sample (NIS) Database 2016-2020 to identify the cohort with principal diagnosis of sinus node dysfunction (SND), atrioventricular block (AVB), and conduction disorder with 1:1 AV conduction using ICD-10-CM codes. For inpatient mortality analysis, COVID-19 patients were excluded from NIS 2020. Outcome analysis included hospitalization rates per 10,000 admissions and adjusted inpatient mortality rate utilizing predictive margins, during each calendar year stratified by sex, age, race, and median household income (MHOI). Results: There were a total of 1,557,806 hospitalizations (713,321 with SND; 297,037 with AVB and 547,448 with conduction disorder with 1:1 AV conduction) with a principal diagnosis of bradyarrhythmia from 2016-2020. Adjusted rates for hospitalizations per 10,000 admissions significantly increased throughout the years 2016-2020 for all three types of bradyarrhythmias, as demonstrated in Figure 1. Between the years 2016 and 2020, adjusted inpatient mortality rates amongst admissions with SND, AVB and conduction disorder with 1:1 AV conduction were similar, p-trend 0.201, 0.823 and 0.965 respectively; demonstrated in Figure 2. Conclusion: Our findings indicate that, throughout the years of 2016-2020, there was a trend suggesting an increase in hospitalization rates for bradyarrhythmias including sinus node dysfunction, atrioventricular block, and conduction disorder with 1:1 AV conduction. These findings may help the healthcare system recognize and decrease the healthcare burden of bradyarrhythmias.