Abstract 15288: The Use of Cha2ds2-vasc Score to Predict Functional Outcomes of Mechanical Thrombectomy

Abstract

Introduction: Mechanical thrombectomy is a widely used form of revascularization for ischemic strokes secondary to large vessel occlusions. Functional outcomes are typically assessed following mechanical thrombectomy using the modified Rankin scale. CHA 2 DS 2 -VASc score is commonly used to estimate the stroke risk of patients with atrial fibrillation, but there are a plethora of studies showing it can be used in various situations. Our study aimed to assess the utility of CHA 2 DS 2 -VASc score in predicting outcomes of patients undergoing mechanical thrombectomy. Methods: We performed a single center, non-randomized, retrospective study. The study included 448 patients that underwent mechanical thrombectomy for large vessel occlusion strokes. CHA 2 DS 2 -VASc score was calculated on each patient and the study population was divided into 3 groups based on CHA 2 DS 2 -VASc score (Score ≤ 2, Score 3-4 and Score ≥ 5). Association between CHA 2 DS 2 -VASc score and 90-day modified Ranking score and in-hospital, 30-day, and one year mortality was evaluated and compared between the three groups. Results: A total of 312 patients met criteria for the study. Patients in the high risk CHA 2 DS 2 -VASc score had a significantly higher modified Rankin score (4.48) when compared to low (2.57) and intermediate (3.82) groups (Image 1). Higher CHA 2 DS 2 -VASc scores were also associated with a significantly higher in-hospital, 30-day, and one year mortality. Conclusion: CHA 2 DS 2 -VASc score can predict worse functional and survival outcomes in patients undergoing mechanical thrombectomy for a large vessel occlusion. CHA 2 DS 2 -VASc score ≥ 5 was associated with higher modified Rankin score and mortality.