Abstract 15115: Causes and Predictors of 90-Day Readmission Among Patients Admitted With Acute Myocarditis

Abstract

Introduction: Myocarditis contributes to the global burden of cardiovascular disease primarily through sudden death and dilated cardiomyopathy. We aimed to study patient characteristics, national readmission rates and predictors for patients admitted for acute myocarditis utilizing a nationally representative cohort of patients from the National Readmission Database. Methods: We utilized the National Readmission Database 2018 to identify the hospitalized adults with a primary diagnosis of acute myocarditis. We included subjects who were readmitted within 90 days after index admission. We excluded subjects with elective and traumatic admissions. We utilized a multivariate cox regression model to identify independent predictors of readmission. Results: During the study period, 3,524 hospitalized patients who had a primary diagnosis of acute myocarditis were discharged alive. Within 90 days of discharge, 356 (10.1%) subjects were readmitted. The top three causes of readmission were heart failure (37.1%), sepsis (16.1%) and ventricular tachycardia (10.6%). The in-hospital mortality rate (5.5 vs. 2.6%, p<0.001) was significantly higher during readmission. There was a trend in higher length of stay in readmission (5.6 vs. 4.3 days, p=0.055), however this difference was not statistically significant. Figure 1 shows the Forest plot of multivariate analysis of independent factors associated with readmissions. Conclusion: Our study identified significant factors such as heart failure, atrial fibrillation, hypertension related to higher readmission odds for myocarditis patients. This data may contribute to the healthcare system to help modify strategies to minimize readmission.