Abstract 14823: Adult Congenital Heart Disease is Associated With a Decreased Prevalence of Morbid Obesity

Abstract

Introduction: Obesity may be associated with greater morbidity in adults with Congenital Heart Disease (ACHD), than in the general population. While obesity prevalence in pediatric CHD has been well studied, the prevalence of obesity in the American ACHD population is unknown. Our study seeks to determine the prevalence of obesity (BMI > 30) and morbid obesity (BMI > 35) in a cohort of ACHD patients, as compared to matched controls. Hypothesis: We assessed the hypothesis that ACHD is associated with a higher prevalence of obesity compared to controls. Methods: Retrospective analysis was performed on all ACHD patients (identified via ICD-9 coding) seen at a tertiary center in 2013. A control group without CHD was randomly created, matching for age, sex, and ethnicity. Results: 1459 ACHD patients met inclusion criteria. ACHD patients had a lower mean BMI than controls (-0.650 kg/m2, 95% CI -1.068 to -0.231, p <0.002). Obesity prevalence did not differ significantly between groups: 25.6% in ACHD, 27.4% in controls (OR 0.909, 95% CI 0.766 to 1.079, p = 0.285). ACHD was associated with lower prevalence of morbid obesity (OR =0.656, CI 0.511 to 0.841, p < 0.0001), and higher prevalence of being underweight (BMI < 18.5) (OR 1.709, 95% CI 1.098 to 2.663, p < 0.016). ACHD was also associated with a lower prevalence of obesity amongst 41-65 year olds (OR = 0.722, 95% CI from 0.561 to 0.929, p < 0.011). Severity of CHD (classified as simple vs. complex) was not significantly related to obesity prevalence. Conclusion: In conclusion, ACHD is associated with a decreased prevalence of morbid obesity, and an increased prevalence of being underweight. ACHD is not significantly associated with obesity prevalence.