Abstract 14799: Home Blood Pressure Range and 24-hr Ambulatory Blood Pressure Control: The Japan Morning Surge Home Blood Pressure (J-HOP) Study-ABPM Substudy

Abstract

Background: Measures of home and ambulatory blood pressure monitoring (HBPM and ABPM) are crucial to evaluate BP control status in hypertensive patients. HBPM is widely used in clinical practice, but ABPM is used less frequently. Few studies have examined the threshold of home BP, suggesting well controlled BP in 24-hour BP, daytime BP, and nighttime BP . Methods: We analyzed data from the Japan Morning Surge Home Blood Pressure (J-HOP) Study, which included 1,439 patients with at least one cardiovascular risk factor (mean age 64.6 years, 47.8% men, 82.3% used antihypertensive medications). Both HBPM (three measures each in the morning and evening over 14 days, using the same semiautomatic HBP device with data memory and 24-hr ABPM were performed in all patients). Results: Of 355 patients with home systolic BP (HSBP) <125mmHg, 78.9%, 76.9%, and 81.4% were classified as having well-controlled 24-hr SBP (<130mmHg), daytime SBP (<135mmHg), and nighttime SBP (<120mmHg), respectively). In contrast, of 656 subjects with HSBP ≥135 mmHg, 67.5% were classified as having uncontrolled 24-hr SBP (≥130mm Hg). Of 428 patients with HSBP between 125mmHg and 134mmHg, only 54.9% were classified as having well-controlled 24-hr SBP. Conclusions: Among patients with high cardiovascular risk, nearly 80% of those with home systolic BP <125mmHg were well-controlled for 24-hr SBP including nighttime systolic BP, whereas nearly 70% of those with >135mmHg were uncontrolled for 24-hr systolic BP. The patients with HBP at 125-134mmHg require ABPM for the evaluation of their 24-hr BP control status.