Abstract 14785: Predictors of In-Hospital Mortality in Coronary Artery Aneurysm Patients: An Insight From the National Inpatient Sample Database

Abstract

Background: There is limited literature on the mortality outcome of coronary artery aneurysms (CAA). The purpose was to study the baseline characteristics, associated co-morbidities, and in-hospital mortality in CAA patients using the Healthcare Cost and Utilization Project National Inpatient Sample database. Methods: The Healthcare Cost and Utilization Project administrative longitudinal database contains encounter-level information on inpatient stays, emergency department visits, and ambulatory surgery in all U.S. hospitals. We performed a cross-sectional analysis on 10230 patients diagnosed with CAA during hospitalization from January 2016 to December 2018. The primary outcome was in-hospital mortality. Results: Of the total patient population, 10230 patients were found to have CAA. All patients with ages ≥ 18 were included in the study (8660). Hypertension, diabetes mellitus, and peripheral vascular disease were predominant co-morbidities. The observed overall in-hospital mortality was 2.9% (251 patients out of 8660). The highest mortality was observed in patients with acute myocardial infarction (adjusted odds ratio: 80.9; 95% confidence interval: 51.9 to 126.1; p-value < 0.01). The age group >80 years had higher mortality when compared to the age group <40 years (adjusted odds ratio: 9.1; 95% confidence interval: 2.9 to 29.3; p-value < 0.00). Smoking (adjusted odds ratio: 46.6; 95% confidence interval: 31.3 to 69.2; p-value < 0.01) and peripheral vascular disease (adjusted odds ratio: 4.0; 95% confidence interval: 2.7 to 6.0; p-value < 0.01) also had a significant impact on mortality (Table 1,2). Conclusion: Our analysis showed higher mortality in CAA with increasing age and in patients who developed acute myocardial infarction, with smoking and peripheral vascular disease also having a significant impact.