Abstract 14437: Incidence and Inpatient Outcomes of Takutsubo Cardiomyopathy in the United States- An Analysis of the National Inpatient Sample

Abstract

Introduction: Takutsubo cardiomyopathy (TC) has been increasingly recognized as an acute cardiac syndrome characterized by typical wall motion abnormality patterns in the absence of epicardial coronary artery disease. It is unknown whether the incidence and mortality of this entity as characterized by race and gender have changed in recent years. Methods: The National Inpatient database (2009-19) was used to study trends in admissions and outcomes of TC over time. Survey estimation commands were used to determine weighted national estimates. Results: During the study period, the estimated incidence rate (IR) per million of hospital admissions for TC was found to increase with age and was higher for women than men in all age distributions (p<0.001). The increase in incidence continued well into older age groups, including patients 85 years and older (Figure). Men with TC were found to have higher rates of in-hospital mortality as compared to women (13.7% vs 7.4%, respectively), however there was no difference in in-hospital mortality when compared by race in both women and men (p=0.376 and p=0.406, respectively). Conclusions: The incidence of TC has increased in both men and women of all races during the study period. There was no difference in in-hospital mortality amongst the different races, however men had higher in-hospital mortality when compared to women.