Abstract

Introduction: Cardiac arrest (CA) remains an important health issue in the United States. Mortality trends of CA death from 1999 to 2018 has been previously published by the American Heart Association. We aim to update the age-specific mortality rates for 2019 and temporal trend in mortality of any-mention cause of CA death from 1999 to 2019. Additionally, we sought to describe the temporal trends of gender and race. Methods: The United States statistics mortality data from 1999 to 2019 were analyzed. A retrospective population-based study was conducted through a search within the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) database. This was performed using the ICD-10 Codes: I46.0, I46, I46.9 and I49.0. Mortality rate was calculated for all the group of ages. Age-adjusted rate was reported for gender and race, crude rate was stated for age group. Poisson regression was used to calculate incidence rate ratio and analyze the temporal trend. Negative binomial regression was used for over dispersed data. Results: We identified 7 435 677 subjects with any-mention of cardiac arrest death from 1999 to 2019. The age-adjusted mortality rate for 1999 was 91.2 compared to 94.7 in 1998. Furthermore, from 1999 to 2019, the trend continues to decrease in CA-related deaths depicted by a gradual decline in the age adjusted mortality rate per year (IRR 0.97 95 % CI 0.95 to 0.99]). Gender age-adjusted mortality rate was higher in males compared to females (126.7 vs 91.3 [IRR 1.39 95 % CI 1.27 to 1.52]). The black/African American population had higher death rates for CA than white (156.9 vs 101.5 [IRR 1.57 95% CI 1.43 to 1.73]) followed by Asian/Pacific Islander (100.5) and American Indian/Alaska Native (80.5). Conclusions: In the period between 1999 and 2019, CA age adjusted mortality rate showed a significant gender and racial disparity. The significant difference in death rates among different racial groups warrants additional investigation. The present surveillance data demonstrates a gradual 10-year decline of CA-related mortality. The increased awareness of CA through public health education, social media and bystanders trained, are thought to play an important factor in the decline of CA deaths.

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