Abstract 14352: Echocardiographic Findings With Troponemia and Its Correlation in COVID-19 Patients

Abstract

Introduction: Echocardiogram findings with Troponemia and its correlation in COVID 19 patients are not well studied Methods: Mean and standard deviation (SD) for continuous variables with normal distribution were reported. Pearson chi-square was performed to see the clinical correlation of dependent variables including regional wall motion abnormalities (RWMA), diastolic dysfunction (DF), paradoxical septal wall motion (PSWM) and pericardial effusion in COVID-19. The primary outcome was to observe the effect on in-hospital mortality and 1 year mortality of echocardiographic findings. Our secondary outcome was to retrospectively see the association of gender with echocardiographic findings. Results: In this small, retrospective, single-center study from an epicenter city of COVID-19 at the Detroit Medical Center. We included a total of 122 patients with confirmed COVID-19. The mean age of the cohort was 67.3 years SD= 14. The mean troponin (Tn) at baseline admission was 173 ng/l SD±762 (normal=3-17 ng/l), while the peak Tn were 693 SD±2941. The baseline RSVP was 16 SD±20, while the peaked RSVP was 4 SD±13. Statistically significant associations of RWMA are shown in figure 1. We also found statistically significant differences in DF with presence of MVR (21/35; p<0.05), and RWMA (event/total; 14/35; p<0.05). We also found significance for RV dilation on initial echo for RVH (11/31; p<0.05), and peaked MVR (6/31; p<0.05). We also found statistically significant differences of PSWM for inpatient mortality (3/3; p<0.05), RVH ( 2/ 3; p <0.05), and LTVMV (3/3 ; p <0.05). We found statistical significance of pericardial effusion and LTVMV (3/14; p <0.05). We found statistical significant correlation of gender and RVH on admission echocardiogram: (Male 15/79; Female 2/43; p<0.05), and RWMA (Male 7/79; Female 0/43; p<0.05). Conclusion: COVID-19 patients have high mortality in the presence of RWMA and PSWM