Abstract 14097: State-Wise Burden of Alcohol-Induced Cardiomyopathy in the United States From 1990-2019: Results From the Global Burden of Disease Study 2019

Abstract

Introduction: Alcoholic cardiomyopathy (ACM) causes 140,000+ alcohol-related deaths yearly. Alcohol consumption and the burden of ACM vary significantly across states within the US. Methods: To assess the burden of ACM in the USA, we used the Global Health Data Exchange. Adult alcohol per capita consumption was obtained from the National Institute on Alcohol Abuse and Alcoholism. Results: Over 30 years, ACM prevalence increased by around 53.15%, reaching 198000(k). Only three US states experienced a decline in the Age-Standardized Prevalence (ASP): the District of Columbia (DC), Maryland, and Virginia. New Hampshire and Utah had the highest and lowest ASP rates, correlating with per capita alcohol consumption. Notably, total US deaths decreased by 9.7%. This decrease is primarily due to a significant reduction in female mortality by about 70%, while mortality in men continues to increase steadily. In DC, Maryland, and Hawaii, females showed the most significant improvement, with DC having the highest reduction in Age-Standardized Death Rates (ASDR) by 83%. South Dakota had the lowest ASDR for both sexes, with 25.6% and 71.88% reductions in males and females, respectively. The Age-Standardized rate of Disability-Adjusted Life Years (ASDALYs) in the US has shown a slight downward trend and has decreased to 174k. However, ASDALYs for males increased by 8.5%. DC continues to have the highest ASDALYs, but with a significant reduction (64%), while South Dakota remained the state with the lowest ASDALYs per 100k, dropping from 35.3 to 22.84. Conclusions: Significant disparities were observed among states, with a higher burden in males. However, these trends were not as pronounced among females, except for increased prevalence. Notably, states with higher per capita alcohol consumption showed a more significant burden of ACM. Targeted interventions aimed at high-risk populations can play a crucial role in reducing the morbidity and mortality associated with this disease.