Abstract 14027: The Use of Anthropometric Indices as Indicators of Hypertension in Patients With Diabetes Types 2: A Large-Scale Cross-Sectional Study

Abstract

Introduction: Obesity is associated with hypertension and diabetes mellitus (DM), increasing cardiovascular disease risk and mortality. While body mass index (BMI) is widely used to measure obesity, it has several limitations. Therefore, alternative anthropometric indices such as waist circumference (WC), waist-to-height ratio (WHtR), body roundness index (BRI), and a body shape index (ABSI) have been suggested. Hypothesis: This study aims to identify the most effective anthropometric index for predicting hypertension in patients with type 2 DM. Methods: In this cross-sectional study, patients with type 2 DM were included and classified into two groups based on the presence or absence of hypertension. Demographic and clinical data were collected and anthropometric measurements were taken. Multivariate logistic regression analysis was used to identify factors associated with hypertension. Receiver operating characteristic (ROC) curves were performed to determine the diagnostic performance of various anthropometric indices, with a subgroup analysis based on the status of patients DM. Results: The study population included 977 male and 1454 female patients with DM, among whom 50.3% and 67.1% had hypertension. Both male and female patients with hypertension were older, had a longer duration of DM, and had higher anthropometric measurements, blood pressure, and lipid profiles. ROC curve analysis revealed that although all indices could significantly predict hypertension (0.55-0.76 in men and 0.68-74 in women), WHtR and BRI had the highest ability to identify patients with hypertension in men irrespective of DM status being controlled or not. (WHtR: 0.76, 95% confidence interval (CI): 0.73-0.79, BRI: 0.76, 95% CI: 0.73-0.79). WC had the highest diagnostic performance in all female patients and female patients with uncontrolled DM (0.75, 95% CI: 0.72-0.75 and 0.75, 95% CI: 0.72-78, respectively). All indices remained significant in the logistic regression after adjusting for potential confounders. Conclusions: While WHtR and BRI were better predictors of hypertension in men with DM, WC had a better diagnostic performance in women with DM.