Abstract 13982: Ischemic Heart Disease Burden in the United States: Prevalence, Mortality, and Regional Differences From 1990-2019

Abstract

Background: Understanding the burden of IHD in the United States is crucial for informed decision-making and targeted interventions aimed at reducing morbidity and mortality. Aim: To understand the burden of IHD, identify gender disparities and risk factors, explore the relationship between socioeconomic growth and IHD, and analyze risk factor distribution across states. Method: utilizing data from the GBD Study 2019. The study assessed the relationship between IHD and socioeconomic development using SDI and measured the overall impact of IHD using DALYs, considering premature death and disability. Data analysis involved comparing prevalence, mortality, SDI, DALYs, attributable burden, and risk estimation among states. Results: Between 1990 and 2019, there was an improvement in socioeconomic development in all states. Age-standardized rates of disease burden for IHD decreased by 50% with the most significant decline observed in Minnesota. Males had higher burden rates than females in all states, and the southeast region had the highest mortality rates. The prevalence of IHD showed a declining trend with a 37.1% decrease in ASPR from 1990. Metabolic risks were the leading contributors to the disease burden, accounting for 50% of cases, with Mississippi having the highest attributable risk. Arkansas had the highest attributable risk for high cholesterol and smoking. Conversely, Minnesota had the lowest burden of IHD among all states. Conclusion: This study highlights variations in the burden of IHD across US states and emphasizes the need for tailored prevention programs to address specific risk factors and gender differences.