Abstract 13870: Routine Follow Up Coronary Angiography versus Clinical Follow Up Only in Patients With Multi-vessel Disease Following Percutaneous Coronary Intervention With Drug-eluting Stents: 3-year Clinical Follow Up Results

Abstract

Background: It is unclear whether the routine follow up (FU) coronary angiography (CAG) regardless of patient’s symptoms after successful percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) in patients (pts) with multi-vessel disease (MVD) is beneficial or not. Methods: The study population consisted of 642 consecutive MVD pts underwent PCI with unrestricted utilization of DESs from January 2004 to May 2011. Routine FU CAG was performed between 6 to 9 months following index PCI and was decided by individual physician’s discretion. Rests of the pts were clinically followed and ischemic driven events were captured. Clinical events including mortality, myocardial infarction and clinically driven PCI before 9 months were excluded in both groups. Cumulative clinical outcomes up to 3 years were compared between the Routine CAG group (n=374 pts) and the Clinical FU group (n= 268 pts). To adjust potential confounders, a propensity score matched (PSM) analysis was performed using the logistic regression model. Results: After PSM analysis, 2 propensity-matched groups (193 pairs, n = 386 pts, C-statistic=0.744) were generated and the baseline characteristics of the two groups were balanced. At 3 years, the incidence of target lesion revascularization (TLR) and target vessel revascularization (TVR) and major adverse cardiac events (MACEs) was higher in the Routine CAG group than the control group (Table). Conclusions: Despite the expected beneficial effects, routine FU CAG following index PCI with DESs in MVD pts was associated with higher incidence of repeat PCI including TLR and TVR and MACE up to 3 years.