Abstract 133: Influence Of Sex, BMI, And Skin Color On The Accuracy Of Non-Invasive Cuffless Photoplethysmography-Based Blood Pressure Measurements

Abstract

Introduction: Vital signs obtained by photoplethysmography (PPG)-based devices might be influenced by subcutaneous fat and skin color. We assessed the hypothesis that a novel PPG-based wearable monitor provides accurate blood pressure (BP) measurements in ambulatory individuals, coming for a routine BP checkup. Methods: This was a comparison study, conducted using a PPG-based device and cuff-based BP device. Systolic BP (SBP) and diastolic BP (DBP) measurements were stratified based on sex, BMI (<25; 25≤BMI<30; 30≤ kg/m 2 ), and skin color (types 1-3 and 4-6 by the Fitzpatrick scale). Results: A total of 1548 measurements were analyzed. Correlations of SBP and DBP between the devices among males/females were between 0.914-0.987 (p<0.001), and Bland-Altman analysis showed a bias of less than 0.5 mmHg for both sexes. Correlations of SBP and DBP between the devices among BMI groups were between 0.931-0.991 (p<0.001), and Bland-Altman analysis showed a bias of less than 1 mmHg for all. Correlations of SBP and DBP between the devices among the skin color groups were between 0.936-0.983 (p<0.001), and Bland-Altman analysis showed a bias of less than 1 mmHg for all. Conclusions: In conclusion, this study shows similar and high agreements between BP measurements obtained using a PPG-based noninvasive cuffless BP device and a cuff-based BP device across sex, BMI, and skin color groups.