Abstract
Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor that arises from parafollicular C cells of the thyroid gland. It accounts for 1% to 10% of thyroid carcinomas, usually presents in the fifth or sixth decade of life, and there is a female predominance. It can be sporadic or hereditary. Sporadic mostly solitary and located in the posterior part of the thyroid, therefore, can present with compressive symptoms. Usually, it is associated with high levels of calcitonin and carcinoembryonic (CEA), used for diagnosis and surveillance.
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