Abstract 12529: Exercise Patterns and Body Mass Index in a Large Cohort of Patients With Anomalous Aortic Origins of Coronary Arteries

Abstract

Introduction: Anomalous aortic origin of a coronary artery (AAOCA) is the second leading cause of sudden cardiac death in the young. Exercise patterns in relation to BMI and surgery status are lacking. Hypothesis: Exercise patterns are variable in AAOCA and relate to BMI and surgery. Aim: To identify differences in exercise patterns and BMI in patients with AAOCA and their relation to surgery status. Methods: Single-center retrospective study of 573 patients with AAOCA (median age = 11.9 years, IQR 6-15), 63% males. Exercise patterns were classified as recreational or organized/competitive. BMI percentiles were stratified as normal (5 th to ≤ 85 th %ile), overweight (85 th to ≤ 95 th %) and obese (≥ 95 th %ile). Exercise patterns and BMI were compared across demographic parameters, presence of ischemia, and surgery status. Mann-Whitney U test was for non-parametric and χ 2 test for categorical variables. Results: Two-thirds of patients exercise recreationally, 1/3 are overweight (BMI > 85 th %ile) and 20% are obese (BMI >95 th %ile) (Table 1). Those who had surgery were more likely to exercise competitively (24% vs 15%, p=0.026). Myocardial ischemia was more likely in those who were exercise restricted (34% vs 14%, p=<0.001). There was no difference in BMI percentile in those with ischemia or who exercised competitively (Table 2). Conclusion: Most patients with AAOCA exercise recreationally and 1 in 5 is obese. Surgery positively relates to competitive exercise. BMI or exercise patterns are unrelated to ischemia but associated with exercise restriction. Future studies are needed to determine optimal exercise recommendations to promote active lifestyle while minimizing the risk of sudden death.