Abstract 11999: COVID-19 Increases the Risk of New Myocardial Infarction in Patients With Prior Myocardial Infarction

Abstract

Introduction: The pathology of coagulopathy in patients with COVID-19 infection is not fully understood and it is believed to differ from the other critical illness. Hypothesis: we aimed to investigate the incidence and type of thromboembolic events (TEE) and particularly myocardial infarction (MI) in patients who were hospitalized with Covid-19 infection with a prior MI. We hypothesized that Covid-19 infection increases the rate of new TEE in this population regardless of age and gender. Methods: A retrospective analysis was conducted for all adult patients (≥18 years of age) admitted for treatment in quarantine centers with COVID-19 infection and developed TEE during the hospital course between February and August 2020. Patients were categorized based on the history of prior MI, age (<55 vs ≥55) and gender. The type of TEE was specified Results: Between February and August 2020, 16,903 patients with COVD-19 infection were admitted in the country and 210 (1.2%) developed TEE (89% were males, 55% were <55 years old, 72% were south Asians, and 80.5% had prior MI). Out of patients with prior MI, 92.5% developed another MI (Figure 1). DVT and portal vein thrombosis were common than new MI in patients without prior MI (Figure 2). New MI was more evident in young male patients who had prior MI; however, it was also reported in young males with no prior MI. No new MI was noted in females with no prior MI. Conclusions: the rate of TEE, particularly MI, increases after Covid-19 infection in patients with prior MI. Age and gender had great impact on the occurrence of TEE as well.