Abstract 11982: Bariatric Surgery is Associated With Lower Odds of Cardiovascular Diseases and Cardiac Arrhythmias Among Hospitalized Patients With Non-Alcoholic Fatty Liver Diseases: A National Inpatient Sample Study

Abstract

Introduction: Morbid obesity has shown a strong association with nonalcoholic fatty liver disease (NAFLD), both of which convey significant risk for the development of cardiovascular diseases (CVD). Bariatric surgery (BS) has proved to improve NAFLD and mitigate the severity of different CVD subgroups. Research Question: What are the odds of having different CVDs among morbidly obese patients with NAFLD who have undergone BS compared to those who have not. Methods: Using multivariate logistic regression, national inpatient sample (NIS) databased was analyzed from 2016 to 2019 to compare the odds of having CVD among NAFLD patients who have undergone BS and those who NAFLD patients with no prior BS. Results: The BS and non-BS groups consisted of 27,865 and 315,300 NALFD patients, respectively. BS group was significantly younger with a higher frequency of female patients.The white race, in contrast to the black race, was more frequently in the non-BS group. In addition, Medicare was significantly higher in the non-BS group compared to the BS group. BS was independently associated with lower odds of having HFpEF, HFrEF, AMI, stroke, CAD, peripheral vascular diseases, heart valve diseases, cardiac arrest, cardiogenic shock, AF, VF, VT, RBBB, LBBB, first-, second-, and third-degree heart block, complete heart block, and fascicular block (p-value<0.001 for all). After adjusting for demographics and medical comorbidities, BS was independently associated with 18% lower odds of in-hospital mortality (OR:0.82, CI 95% 0.69-0.97, p-value=0.018). The BS group had a significantly lower length of hospital stay (8.7 days vs. 10 days) (p-value<0.001). Conclusion: Bariatric surgery is associated with significantly lower odds of having cardiovascular diseases in-hospital mortality, and length of stay among hospitalized morbidly obese patients with NAFLD.