Abstract #1185202: Pituitary apoplexy following initial dose of Gonadotropin-releasing hormone agonists administration. A case report and review of literature.

Abstract

Gonadotropin-releasing hormone (GnRH) agonists are commonly used for hormonal treatment of advanced prostate cancer. Pituitary apoplexy is a very rare, but life-threatening reaction to this treatment. Onset of symptoms could start as early as an hour after injection. We encountered a patient with known pituitary macroadenoma who developed pituitary apoplexy shortly after leuprolide administration.