Abstract #1185032: A case of early-onset severe hypertriglyceridemia found with monogenic chylomicronemia during adulthood

Abstract

Severe hypertriglyceridemia is defined as a serum triglyceride (TG) level above 1000mg/dL. Compared with moderate hypertriglyceridemia, which is more common, severe hypertriglyceridemia is present in 0.4% of general population. The latter owns a risk of recurrent pancreatitis, and the need of intensive care unit and mortality is higher compared to cases of pancreatitis with normal TG levels. Evaluation of severe hypertriglyceridemia should consist of assessment of underlying conditions and consideration of genetic testing for lipoprotein lipase (LPL) and its regulating genes.