Abstract

Hyponatremia is a known complication after transsphenoidal pituitary surgery (TSS), most commonly caused by syndrome of inappropriate antidiuretic hormone secretion (SIADH) and rarely caused by cerebral salt-wasting (CSW). Differentiating between these two etiologies remains a clinical challenge but is important as they have opposing treatments. We present a case of a man who underwent TSS for nonfunctional pituitary macroadenoma and subsequently developed CSW.

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