Abstract 11812: Hypertrophic Cardiomyopathy, in a Latin American Center

Abstract

Introduction: Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiovascular disorder, however, data from Latin-American countries are scarce. Methods: We conducted a retrospective study to characterize the population with HCM in a cardiovascular care center in Bogotá, Colombia. All cardiac magnetic resonance (CMR) performed between 2017 to 2019 were reviewed. Patients with diagnosis of HCM by imaging findings were included in the analysis. Demographic data, and clinical, and imaging characteristics, were described. Results: A total of 2636 CMR were performed between 2017-2019. The diagnostic criteria for HCM were met in 116 (4,4%) patients. The mean age of diagnosis was 63 YO, 54,3% were male. A family history of sudden cardiac death (SCD) was reported in 12%. The most frequent symptoms were dyspnea and chest pain. 26% had atrial fibrillation (table 1). The main phenotype was septal (70%) (figure 1). Most of the patients with HCM (88%) had some alteration of the mitral valve apparatus. Survival at 5 years was 87%. ICD implantation was required in 12,9% of the patients and a septal myomectomy was performed in 6,8%. Conclusions: HCM was more frequent in our cohort than that reported in the current literature, however, the clinical characteristics and prognosis were similar. In our population, HCM patients were diagnosed later than other cohorts.