Abstract
Hashimoto’s thyroiditis (HT) is an autoimmune thyroid disorder discovered by Hakaru Hashimoto in 1912. The disease, which is the most common cause of hypothyroidism in adults, is characterized by a diffusely enlarged or atrophic thyroid with lymphocytic infiltration and the presence of thyroid autoantibodies. It arises from interactions between genetic, epigenetic, and environmental factors. HT has a prevalence of up to 10% in the US adult population and is more frequent among females. Primary thyroid lymphoma (PTL) is a rare cancer, accounting for less than 5% of all thyroid malignancies, and affecting mainly females.
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