Abstract 11749: Rates of Adverse Cardiovascular Outcomes in Patients With Peripheral Arterial Disease Did Not Vary by Neighborhood Deprivation Estimates

Abstract

Introduction: Socioeconomic factors including neighborhoods with limited resources have a negative impact on cardiovascular outcomes in peripheral arterial disease (PAD) patients. An area deprivation index (ADI) quantifies a region’s socioeconomic conditions, which have been linked to health outcomes. Hypothesis: The patients with PAD living in disadvantaged neighborhoods as identified with higher ADI, will have higher co-morbidities and lower access to treatment, resulting in higher incidence of ST-elevation myocardial infarction (STEMI). Methods: Using electronic medical records, we identified patients with PAD (n=6331), using ICD 10 code of I 70 and I 73, with encounter from January 1, 2019 to June 2, 2021. Patients were stratified into four different groups by ADI. Baseline characteristics, comorbidities and medications were recorded for all patients. Using Wilcoxon Rank Sum Test and Pearson Chi Square tests, descriptive statistics are presented for baseline characteristics and comorbidities in table 1. Results: Patients with PAD with the highest ADI (n=1582), were younger (64 ±12), more likely to be African American (59.5%) and current smokers (41.4%) (p<0.001). There were significant differences in co-morbidities across the four groups of different ADIs (p<0.001), with hypertension (83.9% vs 69.6%), CHF (25.3% vs. 17.7%) and diabetes mellitus (15.1% vs.10.4%) being more common in the group with the highest ADI, compared to the group with the lowest ADI. These patients with the highest ADI, were also more likely to be prescribed aspirin, any antiplatelet, a statin or an ACE inhibitor (p< 0.001), suggesting appropriate access to medical therapy. However, the incidence of STEMI was not statistically significant between the groups (p=0.377). Conclusions: PAD patients living in neighborhoods with higher ADI have higher co-morbidities as compared to those in areas with lower ADI. The incidence of STEMI is low in all groups independent of ADI