Abstract #1165969: The Importance of Early Diagnosis of Cushing Disease

Abstract

Endogenous Cushing syndrome (CS) is an underdiagnosed endocrinologic disorder with an estimated incidence of 0.2-5 per million people per year. CS may present with variable clinical manifestations resulting from excess and continuous secretion of cortisol. Early recognition is key to preventing CS-associated high morbidity and mortality when untreated. Hypercortisolemia may be independent or dependent on the adrenocorticotropic hormone (ACTH) being ACTH-secreting pituitary adenoma, also known as Cushing disease (CD), the most common cause of the latter.