Abstract #1154108: Severe Hypercalcemia with a normal PTHrP level treated with Denosumab in the setting of ATLL

Nirali Shah

doi:10.1016/j.eprac.2022.03.186

Abstract #1154108: Severe Hypercalcemia with a normal PTHrP level treated with Denosumab in the setting of ATLL

Nirali Shah

Open Access

https://doi.org/10.1016/j.eprac.2022.03.186

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Journal: Endocrine Practice

Publication Date: May 1, 2022

#Receptor Activator Of Nuclear Factor Kappa B Ligand #Human T Cell Lymphotropic Virus-1 + Show 8 more

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Abstract

Asymptomatic and symptomatic Human T cell Lymphotropic Virus-1 (HTLV-1) infections and Adult T cell Leukemia and Lymphoma (ATLL) are rare but important causes of hypercalcemia. Here, we describe a case of severe hypercalcemia due to ATLL from HTLV-1 infection treated with denosumab, a monoclonal antibody that inhibits Receptor Activator of Nuclear Factor Kappa B ligand (RANKL).

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