Abstract 1061: Digital phenotyping in pediatric oncology: the development of a mobile application for outpatients follow up

Abstract

Abstract Introduction and aim: Outpatients follow up usually depends on recall of data. This recall is subjective to patients' or gaurdians' memory. Smart phones can capture a lot of data either through inbuilt sensors and connected devices or through the engagement of users. These mobile digital devices brought forth innovative methods of acquiring personal healthcare data. In pediatric oncology, the need for accurate record of serious symptoms while patients are at home is a challenge in outpatients' care. In a step towards collecting real-time events that happened during the outpatient follow up, we develop a smart phone application that can record data actively by patients or their guardians in situ and on time of its occurrence, which can improve the follow up process and facilitate a decision making by the physician that based on objective data more than subjective ones. We aim in this research to generate an easy-to-use mobile application for home follow up of pediatric oncology patients. Methods: Predictive characteristics of digital features either extracted from studies or generated by field experts were reported to map the associations between digital feature and the disease. Identified digital features were aggregated into categories that represent interpretable serious signs. A smart phone application with the identified digital features is developed with the help of Valid Solutions, LLC (Health Technology Limited Liability Company, USA). Expected Results: Early and accurate detection of serious symptoms through in situ and on real-time can help to better delivery of required health care. Conclusion: This research will provide a high level vision on relationships between digital phenotyping and pediatric oncology illnesses and will help to identify gaps requiring further research. It will highlight the digital features with higher value of prediction of serious signs. Citation Format: Abeer Abd Elmoneim, Marwan Aly. Digital phenotyping in pediatric oncology: the development of a mobile application for outpatients follow up [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 1061.