Abstract
Biotin( Vitamin B7) is widely available as an over the counter supplement for skin, hair and nail health. Many immunoassays use the biotin-streptavidin interaction as an immobilizing system, in which biotin can be readily incorporated into a hormone. Ingestion of high doses of biotin has been reported to cause abnormal results in thyroid function tests by this assay interference. Hereby we describe the case of a patient with clinical hypothyroidism but biochemically hyperthyroid due to biotin supplementation.
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