Abstract
Objective: The fluctuations of blood pressure in the acute stage of stroke are associated with neurological deterioration and poor prognosis. Although continuous monitoring of blood pressure changes becomes possible with the emergence of wearable blood pressure monitoring equipment, the accuracy of the equipment is still in doubt. Here, the accuracy of the optoelectronic-based wearable device for blood pressure monitoring in hospitalized patients with acute stroke were investigated and verified. Methods: Thirty-five acute stroke patients in the Department of Neurology of a teaching hospital were recruited. With the blood pressure values measured by bedside ECG monitor as the gold standard, wearables devices (wearable wrist watch) and bedside ECG monitors were monitored sequentially the same upper limb at the same time and recorded every 2 hours during the first 24 hours of admission. Receiver operating characteristic (ROC) curves were employed to determine the optimal cut off points and tests of sensitivity, specificity, kappa coefficients were conducted. Results: The average age of participants (male 17, female 18) was 61.91 ±8.72 years. 414 groups of blood pressure values were measured and ranged from 74/41 to 221/124 mmHg. The kappa value of systolic blood pressure (SBP) measured by wearable wrist watch and bedside ECG monitor was 0.768, with 89.1% sensitivity and 87.7% specificity (Table 1-A). And the kappa value of diastolic blood pressure (DBP) was 0.648, with 94.6% sensitivity and 67.9% specificity (Table 1-B). The area under ROC curve for SBP diagnosis and DBP diagnosis of wearable wrist watches were 0.941 ( p < 0.001, Figure 1-A) and 0.939 ( p < 0.001, Figure 1-B) respectively. There was no significant difference in SBP and DBP between these two methods ( p >0.05, Table 3). Conclusions: The accuracy of wearable wrist watch for measuring patient blood pressure with acute stroke is good enough for ambulatory blood pressure monitoring of acute stroke patients.
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