Abstract 10171: Higher Rates of Major Adverse Cardiac and Cerebrovascular Events in Non-White Patients Among Nationwide Hospitalizations of Young Adults: A Race and Sex-Stratified Analysis

Abstract

Introduction: Cardiovascular disease rates among young adults have been increasingly affected by racial and gender disparities and detailed evidence regarding these differences and their impact on cardiovascular events in young adults hospitalizations remain unknown. Methods: The National Inpatient Sample (Oct2015-2017) was queried to identify young adult hospitalizations (18-44 years). Socio-demographics, comorbidities, and rates of major adverse cardiac and cerebrovascular events (MACCE: all-cause mortality, AMI, cardiac arrest, and stroke) were retrieved for males and females and with a more granular comparative analysis for different racial subgroups. A p<0.05 was considered statistically significant. Results: Of 19,448,301 (median age 31 years [25-37], 69.1% non-elective) young adult hospitalizations, 315,290 (1.6%) were identified with MACCE. Black patients followed by Hispanics were most likely hospitalized non-electively. Overall, the MACCE rate was higher in males than in females. Among males, MACCE were higher (5.3%) in Asian or Pacific Islanders (API), whereas in females, black patients were affected the most (1.3%) (Fig. 1). Traditional cardiovascular comorbidities were more prevalent in black and Native American patients (among both male/females) followed by Hispanic/API whereas Caucasians had higher rates of drug abuse including smoking and depression (p<0.001) (Table 1). Conclusions: Among young hospitalizations, non-white, male patients were more frequently admitted non-electively and had higher rates of cardiovascular comorbidities that could have translated into higher MACCE. Special emphasis needs to be laid on gender and racial differences for CVD disease prevention and risk factor modification in young adults.