Abstract 10084: Acute Myocardial Infarction Related Mortality Stratified by State and Region; 1999-2019

Abstract

Introduction: Acute myocardial infarction (AMI) accounts for significant morbidity and mortality and the mortality may vary across regions and states. The aim of this study was to examine the trends in AMI related deaths stratified by regions in the United States from 1999 to 2019. Methods: We used CDC Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) to access National Vital Statistics System data from 1999 to 2019. AMI related deaths, age >/=25 years were identified from multiple causes of death and were represented as age-adjusted mortality rates (AAMR) per 100,000 population. Joinpoint regression was used to examine changes in trend and annual percentage change (APC) overall and stratified by regions. Results: AAMR was highest in South (91.7) followed by Midwest (88.2), Northeast (77.3), and West (64.6). APC in AAMR decreased across all the regions at variable pace. After initial decline, the decrease in APC in AAMR decelerated in South (-2.7) since 2012, Midwest (-3.0) and Northeast (-4.0) since 2009 and West (-2.7) since 2010. States with AAMRs >90th percentile included Arkansas (180.8), Kentucky (136.3), Mississippi (129.7), Tennessee (123.2), Missouri (121.2) and South Dakota (117.9) and <10th percentile included Alaska (44.0), Nevada (48.0), Minnesota (48.8), Hawaii (53.4), Colorado (54.0) and Montana (54.6). Conclusion: AMI related mortality in elderly has been decreasing at a variable pace in various regions. Significant disparities exist across various regions and states. Further research is needed to examine the underlying causes of these disparities and targeted interventions are required to address these disparities.