Abstract #1004047: A Young Patient Presenting with Bone Pain from Brown Tumors due to Underlying Primary Hyperparathyroidism

Abstract

Brown tumors are focal bone lesions formed by osteoclast and fibroblast proliferation with hemosiderin accumulation causing the brown color. They occur in 3% of secondary hyperparathyroidism and 2% of primary hyperparathyroidism (PHPT). In young patients with PHPT, it is prudent to obtain a thorough family history and consider genetic testing for multiple endocrine neoplasias (MEN), hyperparathyroid-jaw tumor (HPT-JT) syndrome, and familial isolated hyperparathyroidism (FIHP), since preferred surgical management may differ. We present a young man with bone pain who was found to have brown tumors caused by PHPT with negative genetic testing.