Abstract
Dopamine agonist (DA) treatment is the mainstay of therapy for prolactinomas and in many tumors can result in significant decreases in tumor size. DA therapy is not without its risks however, with some patients reporting adverse effects such as nausea, lightheadedness, and rarely increased impulsivity or even psychosis. Here we present a case involving a patient with macroprolactinoma on DA therapy with cabergoline (CBG) who developed psychosis requiring discontinuation of CBG, and eventually transsphenoidal surgery (TPS) as well as stereotactic radiotherapy (STRT) to diminish the effects of his giant prolactinoma.
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