Abstract
Colonic absorption of sodium, potassium, chloride, and water was studied in 8 patients with Crohn's disease of the colon (granulomatous colitis) by a perfusion technique using polyethylene glycol 4000 and radioisotopes as markers. Compared with 3 healthy control subjects, net absorption of sodium, chloride, and water was decreased. Insorption of sodium and water was also decreased; potassium fluxes were not significantly altered. Absorption in 3 patients tested both pre- and postoperatively and in 5 others tested periodically after bypass ileostomy did not improve, despite clinical remission.
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