Abstract

IT has been shown by Watson, Cameron and Witts1 that macrocytic anaemia develops in rats in which a blind self-filling intestinal pouch has previously been formed. They were unable2, however, to demonstrate any anatomical or histological lesion in the alimentary tract. Toon3 found that treatment with aureomycin prevented the appearance of anaemia in 100 per cent of rats, adding weight to Witt's suggestion that the anaemia might be due in some way to the bacterial content of the pouch. Nevertheless, Aitken, Badenoch and Spray4 found a deficiency in fat absorption in rats so operated, whether or not anaemia had developed.

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